I regularly deal with phrases such as "seeking alpha". Sometimes they're positive about beta, sometimes they're negative. The one that was really difficult was when I was editing about a fund that had omega in its name. It's really difficult to hide your laughing at work under those circumstances, particularly as there is no way in hell you're going to explain that to other people.
Re: Dept. of Fandom warps the mind
Possibly even a knotty problem.